SCHEMBL3104713

SCHEMBL3104713

NCCCCCc1ccc2nc3ccc(=O)cc-3oc2c1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.55
CYP1A2 P05177 1/20 0.52
TLR8 Q9NR97 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601681 0.88 APP (0.58) APPCYP1A2TLR8
SCHEMBL738742 0.86 APP (0.59) APPCYP1A2TLR8
SCHEMBL5710520 0.85 APP (0.55) APPCYP1A2
SCHEMBL5681747 0.85 APP (0.55) APPCYP1A2
SCHEMBL10208641 0.82 APP (0.64) APPCYP1A2
SCHEMBL4922053 0.82 APP (0.57) APPCYP1A2
SCHEMBL5710642 0.81 APP (0.54) APPCYP1A2
SCHEMBL5483522 0.81 APP (0.50) APPCYP1A2
SCHEMBL563769 0.79 APP (0.66) APPCYP1A2
SCHEMBL10167845 0.79 APP (0.68) APPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2877591-B1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX SA (FR) 2018-01-10 EP disclosed
EP-2689026-B1 DETECTION OF BACTERIA HAVING A RESISTANCE TO CARBAPENEMS BIOMERIEUX SA (FR) 2017-03-08 EP disclosed
US-9562899-B2 Method of detecting OXA-048 carbapenemase producing bacteria bioMérieux (FR) 2017-02-07 US disclosed
US-20150160211-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX (FR) 2015-06-11 US disclosed
EP-2877591-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA Biomérieux (FR) 2015-06-03 EP disclosed
WO-2014016534-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA bioMérieux (FR) 2014-01-30 WO disclosed
EP-2689027-A1 DETECTION OF BACTERIA HAVING AN ENZYMATIC RESISTANCE TO CARBAPENEMS Biomérieux (FR) 2014-01-29 EP disclosed
EP-2689026-A1 DETECTION OF BACTERIA HAVING A RESISTANCE TO CARBAPENEMS Biomérieux (FR) 2014-01-29 EP disclosed
US-8334112-B2 Medium for detecting and/or identifying bacteria BIOMERIEUX (FR) 2012-12-18 US disclosed
WO-2012131216-A1 DETECTION OF BACTERIA HAVING A RESISTANCE TO CARBAPENEMS bioMérieux (FR) 2012-10-04 WO disclosed
US-20100062467-A1 Medium For Detecting And/Or Identifying Bacteria BIOMERIEUX (FR) 2010-03-11 US disclosed
US-20100062466-A1 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2010-03-11 US disclosed
EP-2111462-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111461-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111460-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
WO-2008104681-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104679-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104680-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
EP-1786828-A1 NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY BIOMERIEUX (FR) 2007-05-23 EP disclosed
WO-2006030119-A1 NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY bioMérieux (FR) 2006-03-23 WO disclosed