Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710520 | 0.87 | APP (0.55) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL5681747 | 0.87 | APP (0.55) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL4922053 | 0.82 | APP (0.57) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL3104713 | 0.81 | APP (0.55) | APPCYP1A2 | |
| SCHEMBL10208641 | 0.78 | APP (0.64) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL6998321 | 0.77 | APP (0.67) | APPCYP1A2RAB9ANPC1 | |
| SCHEMBL21211735 | 0.77 | APP (0.62) | APPCYP1A2RAB9ANPC1 | |
| SCHEMBL21211679 | 0.76 | APP (0.64) | APPCYP1A2RAB9ANPC1 | |
| SCHEMBL10167845 | 0.76 | APP (0.68) | APPCYP1A2RAB9A | |
| SCHEMBL563769 | 0.76 | APP (0.66) | APPCYP1A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196545-B1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| EP-1196545-A1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001007573-A1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | disclosed |