Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167845 | 0.89 | APP (0.68) | APPCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL4922053 | 0.84 | APP (0.57) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL563769 | 0.83 | APP (0.66) | APPCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL738742 | 0.83 | APP (0.59) | APPCYP1A2MAPT | |
| SCHEMBL7601681 | 0.82 | APP (0.58) | APPCYP1A2MAPT | |
| SCHEMBL3104713 | 0.82 | APP (0.55) | APPCYP1A2 | |
| SCHEMBL5681747 | 0.82 | APP (0.55) | APPCYP1A2MAPTPDE3BPDE3A | |
| SCHEMBL5710520 | 0.82 | APP (0.55) | APPCYP1A2MAPTPDE3BPDE3A | |
| SCHEMBL9537836 | 0.80 | APP (0.59) | APPCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL6998321 | 0.80 | APP (0.67) | APPCYP1A2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035359-A1 | PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF | THE WASHINGTON UNIVERSITY (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035359-A1 | PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF | PPOX, CYP4Z1, PRDX2 | APP 3242/4885CYP1A2 12/4885KDM4E 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.