Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGFR | P43088 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922284 | 1.00 | TDO2 (0.55) | TDO2PTGER3PTGER2PTGER1HTT | |
| SCHEMBL1167315 | 0.87 | TDO2 (0.54) | TDO2PTGER3PTGER2PTGER1HTT | |
| SCHEMBL1167316 | 0.87 | TDO2 (0.54) | TDO2PTGER3PTGER2PTGER1HTT | |
| SCHEMBL30632999 | 0.87 | TDO2 (0.54) | TDO2PTGER3PTGER2PTGER1HTT | |
| Hydrochloric Acid SCHEMBL6821177 | 0.86 | TDO2 (0.53) | TDO2PTGER3PTGER2PTGER1HTT | |
| SCHEMBL6798674 | 0.84 | KDM4E (0.45) | TDO2HTTKDM4EMAPTLMNA | |
| SCHEMBL6798679 | 0.84 | KDM4E (0.45) | TDO2HTTKDM4EMAPTLMNA | |
| SCHEMBL29406682 | 0.83 | PTGER3 (0.55) | PTGER3PTGER2PTGER1KDM4ETBXA2R | |
| SCHEMBL7378640 | 0.83 | PTGER3 (0.55) | PTGER3PTGER2PTGER1KDM4ETBXA2R | |
| SCHEMBL7378645 | 0.83 | PTGER3 (0.55) | PTGER3PTGER2PTGER1KDM4ETBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-7381832-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6956129-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | TDO2 1153/4885PTGER3 3931/4885PTGER2 3673/4885 |
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | TDO2 1153/4885PTGER3 3931/4885PTGER2 3673/4885 |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | TDO2 1235/4885PTGER3 3740/4885PTGER2 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.