Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927750 | 0.93 | ACKR3 (0.58) | ACKR3MEN1KMT2AMMP13CXCR3 | |
| SCHEMBL4924768 | 0.93 | ACKR3 (0.50) | ACKR3CACNA1GMEN1KMT2AMMP13 | |
| SCHEMBL4920240 | 0.92 | ACKR3 (0.49) | ACKR3MMP13CXCR3CHRM3THRB | |
| SCHEMBL4921326 | 0.91 | UBE2M (0.49) | CACNA1GMEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL4921760 | 0.91 | TSHR (0.55) | ACKR3CACNA1GCCR3TSHR | |
| SCHEMBL4921834 | 0.90 | UBE2M (0.48) | MEN1KMT2AUBE2MDCUN1D1CHRM3 | |
| SCHEMBL4921293 | 0.89 | ALDH1A1 (0.55) | ACKR3CACNA1GALDH1A1GAA | |
| SCHEMBL4924450 | 0.89 | ACKR3 (0.48) | ACKR3MMP13CXCR3UBE2MDCUN1D1 | |
| SCHEMBL4924870 | 0.89 | MEN1 (0.56) | MEN1KMT2AUBE2MDCUN1D1CHRM3 | |
| SCHEMBL4921420 | 0.89 | HRH3 (0.50) | MEN1KMT2AUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | ACKR3 5/4885CACNA1G 1431/4885MEN1 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.