SCHEMBL492291

SCHEMBL492291

O=S(=O)(O)CCC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
PDE4A P27815 1/20 0.41
LMNA P02545 1/20 0.41
SLC6A6 P31641 1/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 1/20 0.41
APP P05067 1/20 0.38
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27819435 0.97 PTGS1 (0.39) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL216634 0.83 APP (0.46) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL15203858 0.82 PTGS1 (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL4455275 0.81 APP (0.44) PTGS1PDE4ALMNASLC6A6CYP2C19
Ammonia Solution, Strong SCHEMBL19811951 0.81 APP (0.44) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL778506 0.81 APP (0.44) PTGS1PDE4ALMNASLC6A6CYP2C19
Pyridine SCHEMBL29217360 0.81 PTGS1 (0.38) PTGS1TSHRTDP1
Ammonia Solution, Strong SCHEMBL19811888 0.79 APP (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL4759462 0.79 APP (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL19811047 0.79 APP (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143638-A Preparation method of 2-adamantanoic acid-trifluoropropane sulfonic acid-derived high-purity electronic grade photoinduced acid generator 苏州威迈芯材半导体有限公司 2024-12-17 CN claimed
US-20240384065-A1 SILOXANE RESIN COMPOSITION FOR FORMING CURED FILM, CURED FILM, AND METHOD OF PRODUCING POLYSILOXANE TORAY INDUSTRIES, INC. (JP) 2024-11-21 US claimed
WO-2024185458-A1 RESIN COMPOSITION, CURED FILM, METHOD FOR PRODUCING SUBSTRATE WITH PATTERN OF CURED FILM, OPTICAL ELEMENT, AND METHOD FOR PRODUCING POLYSILOXANE 東レ株式会社 2024-09-12 WO claimed
CN-117858927-A Silicone resin composition for forming cured film, and method for producing polysiloxane 东丽株式会社 2024-04-09 CN claimed
WO-2023048062-A1 SILOXANE RESIN COMPOSITION FOR FORMING CURED FILM, CURED FILM, AND METHOD FOR PRODUCING POLYSILOXANE 東レ株式会社 2023-03-30 WO claimed
CN-113871720-A High-safety electrolyte and preparation method and application thereof 厦门大学 2021-12-31 CN claimed
CN-110556509-A Method for performing surface protection and passivation treatment on metallic lithium cathode by using fluorine-containing organic matter, product and application NANJING UNIVERSITY OF TECHNOLOGY 2019-12-10 CN claimed
US-10202360-B2 Therapeutic compounds CELGENE QUANTICEL RESEARCH, INC. (US) 2019-02-12 US claimed
WO-2017184462-A1 THERAPEUTIC COMPOUNDS CELGENE QUANTICEL RESEARCH, INC. (US) 2017-10-26 WO claimed
US-20170298040-A1 THERAPEUTIC COMPOUNDS CELGENE QUANTICEL RESEARCH, INC. 2017-10-19 US claimed
JP-3940358-B2 2007-07-04 JP claimed
WO-2007031721-A1 MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS ASTRAZENECA AB (SE) 2007-03-22 WO claimed
US-6992199-B2 Method for sulphonylating a hydroxylated organic compound RHODIA CHIMIE (FR) 2006-01-31 US claimed
EP-1322601-B1 METHOD FOR SULPHONYLATING A HYDROXYLATED ORGANIC COMPOUND RHODIA CHIMIE SA (FR) 2005-08-03 EP claimed
JP-2004510760-A 2004-04-08 JP claimed
JP-3501455-B2 2004-03-02 JP claimed
US-20040024257-A1 Method for sulphonylating a hydroxylated organic compound CHIMIE, RHODIA (FR) 2004-02-05 US claimed
EP-1322601-A1 METHOD FOR SULPHONYLATING A HYDROXYLATED ORGANIC COMPOUND Rhodia Chimie (FR) 2003-07-02 EP claimed
WO-2002028826-A1 METHOD FOR SULPHONYLATING A HYDROXYLATED ORGANIC COMPOUND RHODIA CHIMIE (FR) 2002-04-11 WO claimed
WO-1993003113-A1 LIQUID-CRYSTAL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1993-02-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202360-B2 Therapeutic compounds EP300, BRDT, BRPF3 PTGS1 1627/4885PDE4A 2724/4885LMNA 1855/4885
US-20170298040-A1 THERAPEUTIC COMPOUNDS EP300, BRDT, BRPF3 PTGS1 1627/4885PDE4A 2724/4885LMNA 1855/4885
US-20040024257-A1 Method for sulphonylating a hydroxylated organic compound TST, SCLY, SDHB PTGS1 3606/4885PDE4A 4832/4885LMNA 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.