Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | THRA | P10827 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927337 | 0.93 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4932449 | 0.90 | HSD17B10 (0.39) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL4932752 | 0.90 | THRB (0.41) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4930987 | 0.90 | THRB (0.41) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL5718090 | 0.89 | THRA (0.49) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4932258 | 0.88 | SMN1; SMN2 (0.43) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4356831 | 0.87 | THRA (0.58) | THRBTHRASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL5116889 | 0.87 | SMN1; SMN2 (0.40) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4930828 | 0.86 | SMN1; SMN2 (0.39) | THRBTHRASMN1; SMN2MAPTRAB9A | |
| SCHEMBL5116634 | 0.86 | BRD4 (0.39) | THRBTHRASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRB 4/4885THRA 3/4885SMN1; SMN2 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.