Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 6/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 5/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156675 | 0.82 | HTR2C (0.41) | POLBSLC16A3ACLYSLC16A1MCTS1 | |
| SCHEMBL1156338 | 0.81 | ACLY (0.39) | SLC16A3ACLYMEN1KMT2ACNR2 | |
| SCHEMBL1156677 | 0.78 | ACLY (0.37) | RXFP1POLBSLC16A3ACLYSLC16A1 | |
| SCHEMBL1580757 | 0.77 | ACLY (0.39) | SLC16A3ACLYKAT8MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1156903 | 0.76 | ACLY (0.39) | SLC16A3ACLYKAT8MEN1KMT2A | |
| SCHEMBL1156674 | 0.76 | ACLY (0.38) | SLC16A3ACLYKAT8PTGDR2 | |
| SCHEMBL1156341 | 0.76 | ACLY (0.41) | ACLYMEN1KMT2APTGDR2 | |
| SCHEMBL4566726 | 0.72 | CTSD (0.31) | RXFP1 | |
| SCHEMBL1156292 | 0.71 | ACLY (0.40) | ACLYMEN1KMT2ACHRM1 | |
| SCHEMBL4566702 | 0.70 | ALDH1A1 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919865-A1 | 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026916-A1 | 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |