Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28771343 | 0.98 | TRPA1 (0.51) | TRPA1TSHRCA1CA2KDM4E | |
| Hydrochloric Acid SCHEMBL3574165 | 0.95 | TRPA1 (0.53) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL30253482 | 0.85 | CYP1A2 (0.48) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL23856748 | 0.85 | CYP1A2 (0.48) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL30940563 | 0.81 | TRPA1 (0.50) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL1033059 | 0.81 | TRPA1 (0.50) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL28730767 | 0.80 | TRPA1 (0.40) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL17954603 | 0.79 | DRD2 (0.46) | TRPA1KDM4EALDH1A1NOTUMDRD2 | |
| SCHEMBL819087 | 0.78 | KCNH2 (0.46) | TRPA1TSHRCA1CA2KDM4E | |
| SCHEMBL30173200 | 0.78 | NOTUM (0.44) | TRPA1TSHRCA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242162-B2 | Sensor group attachec to imide of aromatictetracarboxylic dianhydride; aromatic core may be anthracene, phenanthrene, perylene, or benzo[e]pyrene; sensor groups include crown ethers, aryl amines, porphyrins, and phenylboronic acid; detecting nitroaromatic explosives and chemical warfare agents | OHIO AEROSPACE INSTITUTE (US) | 2012-08-14 | — | — | US | disclosed |
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | OHIO AEROSPACE INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | AHR, PAH, ALK | TRPA1 13/4885TSHR 2244/4885CA1 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.