SCHEMBL4923819

SCHEMBL4923819

O=C(O)c1ccc(S(=O)(=O)c2ccccc2)c(C(=O)O)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
HTR6 P50406 5/20 0.45
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
GFER P55789 1/20 0.42
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
MMP1 P03956 3/20 0.40
MMP2 P08253 3/20 0.40
MMP9 P14780 3/20 0.40
MMP8 P22894 3/20 0.40
MMP13 P45452 3/20 0.40
MMP12 P39900 2/20 0.40
MMP14 P50281 2/20 0.40
MMP16 P51512 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29676384 0.86 NPSR1 (0.47) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL34677 0.86 NPSR1 (0.47) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL27412126 0.85 NPSR1 (0.44) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL689428 0.84 NPSR1 (0.46) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL4962919 0.79 NPSR1 (0.47) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL1296294 0.77 POLB (0.54) NPSR1HTR6ALDH1A1GAAPOLB
SCHEMBL505289 0.77 MMP2 (0.58) NPSR1HTR6ALDH1A1POLBTSHR
SCHEMBL8606449 0.77 HSD17B10 (0.42) ALDH1A1TSHRALOX15KDM4EHPGD
SCHEMBL30705724 0.77 HSD17B10 (0.42) ALDH1A1TSHRALOX15KDM4EHPGD
SCHEMBL11610684 0.76 MMP2 (0.55) TSHRALOX15MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4007146-A POLYESTER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-02-08 US claimed
US-3936404-A Aqueous baking varnishes from carboxylic polyester and carboxylic polyimide, and coated article NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed
US-20080174016-A1 Flexible Printed Wiring Board and Semiconductor Device MITSUI MINING & SMELTING CO., LTD. (JP) 2008-07-24 US disclosed