Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929630 | 0.91 | SUCNR1 (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL5717913 | 0.91 | THRA (0.42) | GAASUCNR1MEN1KMT2ATHRA | |
| SCHEMBL4358268 | 0.90 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4924159 | 0.87 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4931827 | 0.86 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL5718084 | 0.86 | SUCNR1 (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4923176 | 0.85 | THRA (0.40) | SMN1; SMN2LMNAALDH1A1GAAMEN1 | |
| SCHEMBL4929456 | 0.85 | THRB (0.47) | SUCNR1THRATHRBPTPN1 | |
| SCHEMBL4926487 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1GAAMEN1 | |
| SCHEMBL5717921 | 0.83 | THRA (0.34) | SMN1; SMN2LMNAALDH1A1GAASUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | PDE4A 897/4885PDE4B 1391/4885PDE4C 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.