Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936272 | 1.00 | TSHR (0.54) | TSHRCNR1CNR2MCHR1TLR8 | |
| SCHEMBL5108682 | 0.85 | TSHR (0.60) | TSHRCNR1CNR2MCHR1TLR8 | |
| SCHEMBL4428671 | 0.80 | SOAT1 (0.52) | TSHRTLR8PTPN11FYNMEN1 | |
| SCHEMBL989755 | 0.80 | TSHR (0.50) | TSHRMCHR1TLR8MEN1MAPT | |
| SCHEMBL28103222 | 0.80 | TSHR (0.50) | TSHRMCHR1TLR8MEN1MAPT | |
| SCHEMBL14706339 | 0.74 | TSHR (0.45) | TSHRMCHR1TLR8MEN1MAPT | |
| SCHEMBL4910078 | 0.74 | TSHR (0.56) | TSHRMCHR1TLR8PTPN11MEN1 | |
| SCHEMBL4909965 | 0.74 | TSHR (0.56) | TSHRMCHR1TLR8PTPN11MEN1 | |
| SCHEMBL4908833 | 0.74 | TSHR (0.56) | TSHRMCHR1TLR8PTPN11MEN1 | |
| SCHEMBL18675930 | 0.73 | TSHR (0.79) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269458-A1 | POLYIMIDE AND LIQUID CRYSTAL ALIGNMENT FILM THEREOF | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269458-A1 | POLYIMIDE AND LIQUID CRYSTAL ALIGNMENT FILM THEREOF | PUF60, DDT, PARG | TSHR 4533/4885CNR1 4841/4885CNR2 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.