Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924153 | 0.85 | TSHR (0.54) | TSHRCNR1CNR2MCHR1TLR8 | |
| SCHEMBL4936272 | 0.85 | TSHR (0.54) | TSHRCNR1CNR2MCHR1TLR8 | |
| SCHEMBL18675930 | 0.78 | TSHR (0.79) | TSHRCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5107815 | 0.76 | CYP19A1 (0.52) | PTPN11MEN1MAPTKMT2ALMNA | |
| SCHEMBL7713999 | 0.76 | THRA (0.53) | CNR2PTPN11MEN1MAPTKMT2A | |
| SCHEMBL11546346 | 0.76 | TSHR (1.00) | TSHRCYP3A4TP53 | |
| SCHEMBL17402431 | 0.76 | TSHR (1.00) | TSHRCYP3A4TP53 | |
| SCHEMBL4909965 | 0.76 | TSHR (0.56) | TSHRMCHR1TLR8PTPN11CYP1A2 | |
| SCHEMBL21295950 | 0.76 | TSHR (1.00) | TSHRCYP3A4TP53 | |
| SCHEMBL5145915 | 0.76 | TSHR (1.00) | TSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7318964-B2 | Fluorene compounds containing various functional groups, polymers thereof and EL element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-15 | — | — | US | claimed |
| US-7318964-B2 | Fluorene compounds containing various functional groups, polymers thereof and EL element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-15 | — | — | US | disclosed |
| US-20030091859-A1 | Fluorene compounds containing various functional groups, polymers thereof and el element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091859-A1 | Fluorene compounds containing various functional groups, polymers thereof and el element using the same | AFF4, AFF2, LEF1 | TSHR 4411/4885CNR1 4549/4885CNR2 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.