Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431430 | 0.89 | PTGDR2 (0.42) | SOAT1TLR8CDC7PLK4CHEK1 | |
| SCHEMBL28049521 | 0.82 | ALDH1A1 (0.46) | TSHRTLR8THRBMAPK1CYP1A2 | |
| SCHEMBL4924153 | 0.80 | TSHR (0.54) | SOAT1TSHRTLR8PTPN11MAP4K4 | |
| SCHEMBL4936272 | 0.80 | TSHR (0.54) | SOAT1TSHRTLR8PTPN11MAP4K4 | |
| SCHEMBL27495357 | 0.78 | SOAT1 (0.49) | SOAT1PTPN1THRATHRBLTA4H | |
| SCHEMBL7789312 | 0.78 | SOAT1 (0.49) | SOAT1TSHRPTPN1THRATHRB | |
| SCHEMBL9621759 | 0.77 | CYP1A2 (0.46) | SOAT1PTPN1TLR8LTA4HCDC7 | |
| SCHEMBL7926353 | 0.77 | SOAT1 (0.50) | SOAT1PTPN1LTA4HPTPN11CYP2C9 | |
| SCHEMBL4432989 | 0.76 | FAAH (0.46) | SOAT1THRATHRBPTPN11HDAC8 | |
| SCHEMBL9068422 | 0.75 | KDM4E (0.49) | SOAT1PTPN1THRATHRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589245-B2 | Process for preparing linear alpha olefins | SHELL OIL COMPANY (US) | 2009-09-15 | — | — | US | disclosed |
| US-7589245-B2 | Process for preparing linear alpha olefins | SHELL OIL COMPANY (US) | 2009-09-15 | — | — | US | disclosed |
| US-7547783-B2 | Transition metal complexes | SHELL OIL COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547783-B2 | Transition metal complexes | SHELL OIL COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| EP-1765748-B1 | PROCESS FOR PREPARING LINEAR ALPHA OLEFINS | SHELL INT RESEARCH (NL) | 2008-09-24 | — | — | EP | disclosed |
| EP-1740598-B1 | TRANSITION METAL COMPLEXES | SHELL INT RESEARCH (NL) | 2008-03-05 | — | — | EP | disclosed |
| EP-1765748-A1 | PROCESS FOR PREPARING LINEAR ALPHA OLEFINS | Shell Internationale Research Maatschappij B.V. (NL) | 2007-03-28 | — | — | EP | disclosed |
| EP-1740598-A1 | TRANSITION METAL COMPLEXES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2007-01-10 | — | — | EP | disclosed |
| EP-1542797-B1 | CATALYST SYSTEMS FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INT RESEARCH (NL) | 2006-05-31 | — | — | EP | disclosed |
| US-7053020-B2 | Catalyst systems for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| WO-2006005762-A1 | PROCESS FOR PREPARING LINEAR ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2006-01-19 | — | — | WO | disclosed |
| US-20060014989-A1 | Process for preparring linear alpha olefins | SHELL OIL COMPANY | 2006-01-19 | — | — | US | disclosed |
| US-20050215792-A1 | Transition metal complexes | SHELL OIL COMPANY | 2005-09-29 | — | — | US | disclosed |
| WO-2005090371-A1 | TRANSITION METAL COMPLEXES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2005-09-29 | — | — | WO | disclosed |
| EP-1542797-A2 | CATALYST SYSTEMS FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2005-06-22 | — | — | EP | disclosed |
| US-20040116758-A1 | Catalyst systems for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY | 2004-06-17 | — | — | US | disclosed |
| WO-2004037415-A2 | CATALYST SYSTEMS FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215792-A1 | Transition metal complexes | NCLN, PRNP, PARN | SOAT1 4257/4885TSHR 3597/4885PTPN1 228/4885 |
| US-20060014989-A1 | Process for preparring linear alpha olefins | ITGAL, CCNL2, TRA2B | SOAT1 315/4885TSHR 3485/4885PTPN1 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.