SCHEMBL492432

SCHEMBL492432

CCCN1CCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148599 0.87 KMT2A (0.63)
SCHEMBL9614696 0.87 SMN1; SMN2 (0.50)
SCHEMBL13236669 0.85 ALDH1A1 (0.50)
SCHEMBL3420576 0.85 KMT2A (0.56)
SCHEMBL6890835 0.84 KMT2A (0.55)
SCHEMBL6269938 0.84 KMT2A (0.55)
SCHEMBL8587006 0.84 KMT2A (0.55)
SCHEMBL6561471 0.84 KMT2A (0.55)
SCHEMBL8671910 0.84 KMT2A (0.55)
SCHEMBL10745323 0.84 KMT2A (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200047110-A1 ACIDIC GAS ABSORBENT, ACIDIC GAS REMOVAL METHOD AND ACIDIC GAS REMOVAL APPARATUS KABUSHIKI KAISHA TOSHIBA (JP) 2020-02-13 US claimed
JP-2901297-B2 1999-06-07 JP claimed
EP-0378657-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. RAJADHYAKSHA VITHAL J 1990-07-25 EP claimed
WO-1990000407-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS RAJADHYAKSHA VITHAL J (US) 1990-01-25 WO claimed
CN-118159256-A Diclofenac-containing TTS with dimethylpropyleneurea LTS勒曼治疗系统股份公司 2024-06-07 CN disclosed
WO-2024092011-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-05-02 WO disclosed
WO-2024057277-A1 DIAGNOSTIC PET IMAGING OF CARDIAC AMYLOIDOSIS Beijing Lado Technology Co., Ltd. (CN) 2024-03-21 WO disclosed
US-20230220275-A1 METHOD FOR PRODUCING INORGANIC FLUORIDE LUMINESCENT MATERIAL NICHIA CORPORATION (JP) 2023-07-13 US disclosed
US-20230142294-A1 PRODUCTION METHOD OF INORGANIC FLUORIDE LUMINESCENT MATERIAL NICHIA CORPORATION (JP) 2023-05-11 US disclosed
WO-2023079118-A1 DICLOFENAC-CONTAINING TTS COMPRISING DIMETHYLPROPYLENEUREA LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2023-05-11 WO disclosed
US-20230136702-A1 Inhibitors of Human Herpesviruses THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) 2023-05-04 US disclosed
EP-3258925-B1 METHODS AND COMPOSITIONS FOR DECREASING GASTRIC EMPTYING PURDUE PHARMA LP (US) 2023-03-29 EP disclosed
WO-2007022258-A1 NOVEL HIGH AFFINITY THIOPHENE-BASED AND FURAN-BASED KINASE LIGANDS SCHERING CORPORATION (US) 2007-02-22 WO disclosed
EP-1228070-B1 HETEROALKYLAMINO-SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE HOFFMANN LA ROCHE (CH) 2007-02-07 EP disclosed
US-7018964-B2 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-28 US disclosed
WO-2005090291-A1 ION CHANNEL MODULATORS WYETH (US) 2005-09-29 WO disclosed
US-20030181349-A1 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-25 US disclosed
EP-1295935-A1 DETERGENT COMPOSITION Arakawa Chemical Industries, Ltd. (JP) 2003-03-26 EP disclosed
EP-1068200-A1 2,4,4-TRISUBSTITUTED-1,3-DIOXOLANE ANTIFUNGALS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-17 EP disclosed
WO-1999002523-A1 2,4,4-TRISUBSTITUTED-1,3-DIOXOLANE ANTIFUNGALS JANSSEN PHARMACEUTICA N.V. (BE) 1999-01-21 WO disclosed