SCHEMBL4925003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4932374	0.85	HDAC1 (0.62)	HDAC1HDAC4KCNH2ALDH1A1HDAC6
	SCHEMBL4932367	0.85	HDAC1 (0.62)	HDAC1HDAC4KCNH2ALDH1A1HDAC6
	SCHEMBL29196444	0.82	HDAC1 (0.84)	HDAC1HDAC4KCNH2HDAC6HDAC8
	SCHEMBL28742702	0.80	HDAC1 (0.81)	HDAC1HDAC4KCNH2ALDH1A1HDAC6
	SCHEMBL2195779	0.79	MEN1 (0.69)	HDAC1HDAC4KCNH2ALDH1A1GAA
	SCHEMBL12341280	0.77	HDAC1 (0.81)	HDAC1HDAC4KCNH2HDAC6HDAC8
	SCHEMBL12472215	0.77	HDAC6 (1.00)	HDAC1HDAC4KCNH2HDAC6HDAC8
	SCHEMBL445115	0.77	HDAC1 (0.62)	HDAC1HDAC4KCNH2ALDH1A1HDAC6
	SCHEMBL26159154	0.77	HDAC1 (1.00)	HDAC1HDAC4KCNH2HDAC6HDAC8
	SCHEMBL30518143	0.76	GRIN2B (0.69)	HDAC1HDAC4KCNH2ALDH1A1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.