Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807847 | 0.93 | SLC6A3 (0.58) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL29552558 | 0.93 | SLC6A3 (0.63) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL4780476 | 0.93 | SLC6A3 (0.63) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL4742182 | 0.91 | SLC6A3 (0.66) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL13344069 | 0.88 | SLC6A4 (0.46) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL2225745 | 0.88 | PRKACA (0.52) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3493099 | 0.87 | SLC6A4 (0.45) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL27167132 | 0.84 | SLC6A4 (0.41) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL21200393 | 0.82 | ALDH1A1 (0.39) | MAOAMAOBTAAR1SLC6A4SLC6A3 | |
| SCHEMBL29575175 | 0.82 | ALDH1A1 (0.39) | MAOAMAOBTAAR1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063114-A9 | AMINO- IMIDAZOLONES AND THEIR USE AS MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA | ASTRAZENECA AB (SE) | 2008-09-04 | — | — | WO | disclosed |