Iophendylate

Iophendylate

SCHEMBL492663

CCOC(=O)CCCCCCCCC(C)c1ccc(I)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.42
CYP4A11 Q02928 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 3/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.39
NAMPT P43490 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 1/20 0.38
TBXAS1 P24557 1/20 0.37
CYP4Z1 Q86W10 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iophendylate SCHEMBL15532920 0.92 MAPT (0.41) CYP4F2CYP4A11KMT2AMEN1ALDH1A1
SCHEMBL7708867 0.80 CYP3A4 (0.53) CYP4F2CYP4A11TDP1ALDH1A1CYP3A4
SCHEMBL31615146 0.79 ALDH1A1 (0.44) TDP1KMT2AMEN1ALDH1A1ALOX15
SCHEMBL8902332 0.79 ALOX15 (0.55) TDP1KMT2AMEN1ALDH1A1ALOX15
SCHEMBL3936803 0.78 CYP4F2 (0.46) CYP4F2CYP4A11TDP1KMT2AALDH1A1
SCHEMBL492664 0.78 CYP4F2 (0.46) CYP4F2CYP4A11TDP1KMT2AALDH1A1
SCHEMBL25969333 0.78 CYP4F2 (0.43) CYP4F2CYP4A11TDP1KMT2AMEN1
SCHEMBL5962655 0.77 NAMPT (0.41) CYP4F2CYP4A11TDP1KMT2AMEN1
SCHEMBL1263477 0.77 CYP4Z1 (0.58) CYP4F2CYP4A11TDP1ALDH1A1ALOX15
SCHEMBL9559017 0.77 CYP4Z1 (0.58) CYP4F2CYP4A11TDP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 921 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170280-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
US-20250170279-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
WO-2025052207-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY AND METHOD FOR THEIR REALIZATION TECRES S.P.A. (IT) 2025-03-13 WO claimed
US-20230414836-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY TECRES S.P.A. (IT) 2023-12-28 US claimed
WO-2021238893-A1 EFFICIENT AND EFFECTIVE TISSUE CLEARING AGENTS AND THEIR COMPOSITIONS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-12-02 WO claimed
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2021-05-20 US claimed
US-20200397926-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE,PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2020-12-24 US claimed
EP-3744317-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF Beijing Inno Medicine Co., Ltd. (CN) 2020-12-02 EP claimed
US-10600524-B2 Radiation protection device and methods thereof STEMRAD LTD. (IL) 2020-03-24 US claimed
EP-3610859-A1 CERASOME DELIVERY SYSTEM FOR USE IN TARGETED ACTIVATION OF CD44 MOLECULE, PREPARATION METHOD THEREFOR AND USE Beijing Inno Medicine Co., Ltd. (CN) 2020-02-19 EP claimed
EP-0414806-A1 HIGH RATIO ACTIVE AGENT:LIPID COMPLEX. LIPOSOME CO INC (US) 1991-03-06 EP claimed
EP-0165994-B1 CONTRAST AGENTS AND METHOD OF USE THEREOF RUBIN, Daniel Lee (US) 1990-07-18 EP claimed
WO-1989011272-A1 HIGH RATIO ACTIVE AGENT:LIPID COMPLEX THE LIPOSOME COMPANY, INC. (US) 1989-11-30 WO claimed
EP-0165630-B1 METHOD OF PREPARING A CHLORINATED, BROMINATED, RADIOBROMINATED, IODINATED AND/OR RADIOIODINATED, AROMATIC OR HETEROAROMATIC COMPOUND, AS WELL AS A KIT FOR PREPARING A DIAGNOSTIC COMPOSITION ON THE BASIS OF THIS COMPOUND MALLINCKRODT, INC.(a Missouri corporation) (US) 1989-10-18 EP claimed
CN-86107191-A Vascular occlusive agent (TH glue) 1988-04-27 CN claimed
EP-0165994-A4 CONTRAST AGENTS AND METHOD OF USE THEREOF. RUBIN DANIEL LEE 1986-11-07 EP claimed
EP-0165994-A1 CONTRAST AGENTS AND METHOD OF USE THEREOF. RUBIN DANIEL LEE 1986-01-02 EP claimed
EP-0165630-A2 Method of preparing a chlorinated, brominated, radiobrominated, iodinated and/or radioiodinated, aromatic or heteroaromatic compound, as well as a kit for preparing a diagnostic composition on the basis of this compound MALLINCKRODT, INC.(a Missouri corporation) (US) 1985-12-27 EP claimed
WO-1985003004-A1 CONTRAST AGENTS AND METHOD OF USE THEREOF RUBIN DANIEL LEE 1985-07-18 WO claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF CD44, LDLR, PLAUR CYP4F2 4744/4885CYP4A11 3295/4885TDP1 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.