Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922707 | 0.93 | HIF1A (0.56) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4586922 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4931705 | 0.91 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4927908 | 0.91 | HIF1A (0.54) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4923602 | 0.90 | HIF1A (0.53) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| Dimethylamine SCHEMBL4923606 | 0.90 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4932283 | 0.90 | HIF1A (0.54) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL4929390 | 0.89 | HIF1A (0.52) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL3946651 | 0.87 | BRD4 (0.53) | ALDH1A1BRD4SERPINE1MEN1KMT2A | |
| SCHEMBL4929352 | 0.87 | HIF1A (0.54) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004268-A1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | NGUYEN DUY | 2008-01-03 | — | — | US | disclosed |
| US-20060074084-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004268-A1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | ADCY1, ADCY2, ADCY5 | ALDH1A1 268/4885HPGD 135/4885CYP1A2 1151/4885 |
| US-20060074084-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCY5 | ALDH1A1 268/4885HPGD 135/4885CYP1A2 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.