SCHEMBL4927962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4929207	0.89	ACKR3 (0.52)	MEN1KMT2AACKR3HDAC1LMNA
	SCHEMBL4925724	0.87	ACKR3 (0.52)	MEN1KMT2AACKR3HDAC1LMNA
	SCHEMBL4923237	0.85	ACKR3 (0.57)	ACKR3HDAC1HDAC3HDAC4HDAC7
	SCHEMBL4931575	0.84	AKT3 (0.64)	ACKR3HDAC1HDAC3HDAC4HDAC7
	SCHEMBL4929284	0.83	HDAC1 (0.58)	KMT2AACKR3HDAC1HDAC3HDAC4
	SCHEMBL4927375	0.83	ACKR3 (0.57)	MEN1KMT2AACKR3HDAC1HDAC3
	SCHEMBL16712965	0.81	ROCK2 (0.66)	MEN1KMT2AHDAC1LMNAPTPN7
	SCHEMBL4923388	0.80	ACKR3 (0.67)	ACKR3HDAC1HDAC3HDAC4HDAC7
	SCHEMBL4929057	0.80	ACKR3 (0.57)	KMT2AACKR3HDAC1LMNAHDAC3
	SCHEMBL5003505	0.80	AKT3 (0.76)	MEN1KMT2AHDAC1AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.