Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927974 | 1.00 | CISD1 (0.50) | CISD1MGAMGAASIMGAM2 | |
| SCHEMBL4930632 | 0.93 | HPGD (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL4930628 | 0.93 | HPGD (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL8252319 | 0.93 | HPGD (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL8246468 | 0.89 | MMP3 (0.53) | MGAMGAASIMGAM2PIK3CG | |
| SCHEMBL4928465 | 0.89 | MMP3 (0.53) | MGAMGAASIMGAM2PIK3CG | |
| SCHEMBL3757967 | 0.89 | CISD1 (0.51) | CISD1MGAMGAASIMGAM2 | |
| SCHEMBL3757966 | 0.89 | CISD1 (0.51) | CISD1MGAMGAASIMGAM2 | |
| SCHEMBL12997325 | 0.89 | CISD1 (0.51) | CISD1MGAMGAASIMGAM2 | |
| SCHEMBL4928473 | 0.85 | ADAMTS5 (0.44) | GAAPIK3CGADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267888-A1 | Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | claimed |
| WO-2006126074-A2 | HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | WO | claimed |
| US-20080267888-A1 | Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| WO-2006126074-A2 | HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267888-A1 | Heterocyclic Derivatives | CYP11B2, MAPT, UGT1A1 | CISD1 2304/4885MGAM 3515/4885GAA 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.