SCHEMBL4928010

SCHEMBL4928010

CCCN(CCC)CCC[C@H](N)C(=O)NO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 9/20 0.45
SLC15A1 P46059 1/20 0.45
DPP8 Q6V1X1 7/20 0.41
DPP9 Q86TI2 7/20 0.41
DPP4 P27487 4/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
RRM1 P23921 1/20 0.38
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
METAP1 P53582 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4926973 0.92 DPP7 (0.51) DPP7SLC15A1DPP8DPP9DPP4
SCHEMBL243605 0.81 DPP7 (0.63) DPP7SLC15A1DPP8DPP9DPP4
SCHEMBL5574688 0.78 GNAI3 (0.60) DPP7SLC15A1DPP8DPP9DPP4
SCHEMBL247697 0.77
SCHEMBL30117075 0.77
SCHEMBL1638425 0.76 NOD1 (0.41) DPP7SLC15A1NOS3NOS1NOS2
SCHEMBL24642458 0.75 GSR (0.52) NOS3NOS1NOS2
SCHEMBL4934859 0.73 DPP7 (0.42) DPP7DPP8DPP9HDAC7HDAC8
SCHEMBL16572365 0.72 DPP7 (0.56) DPP7SLC15A1GNAI3GNAO1GNAI1
SCHEMBL7907464 0.72 DPP7 (0.53) DPP7SLC15A1DPP8DPP9DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080132539-A1 Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative KUREHA CORPORATION (JP) 2008-06-05 US disclosed
EP-1707560-A1 HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE Kureha Corporation (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132539-A1 Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative HDAC5, HDAC1, HDAC9 DPP7 275/4885SLC15A1 1441/4885DPP8 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.