Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | CSK | P41240 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987663 | 0.73 | HDAC3 (0.43) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4928010 | 0.73 | DPP7 (0.45) | DPP7DPP8DPP9HDAC8HDAC6 | |
| SCHEMBL4926973 | 0.72 | DPP7 (0.51) | DPP7DPP8DPP9HDAC8HDAC6 | |
| SCHEMBL8987683 | 0.70 | HDAC3 (0.46) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4928103 | 0.68 | NPC1 (0.57) | MMP9 | |
| SCHEMBL4928980 | 0.68 | HDAC6 (0.50) | HDAC8HDAC3HDAC1HDAC2MMP2 | |
| SCHEMBL209885 | 0.67 | DPP7 (0.66) | DPP7DPP8DPP9HDAC8HDAC3 | |
| SCHEMBL8360814 | 0.66 | KCNH2 (0.50) | DPP7MMP2 | |
| SCHEMBL8360812 | 0.66 | KCNH2 (0.50) | DPP7MMP2 | |
| SCHEMBL8360817 | 0.66 | KCNH2 (0.50) | DPP7MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | DPP7 275/4885DPP8 229/4885DPP9 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.