SCHEMBL4928176

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4919672	0.88	ACKR3 (0.59)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4922556	0.86	HDAC3 (0.59)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4930312	0.86	ESRRG (0.74)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4929840	0.86	ESRRG (0.56)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4929172	0.86	HDAC1 (0.59)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4929351	0.86	ACKR3 (0.58)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4932331	0.86	DYRK1A (0.59)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4919982	0.85	ROCK1 (0.69)	ROCK2ROCK1ACKR3MMP13CYP3A4
	SCHEMBL4924579	0.85	HDAC3 (0.68)	ROCK2ROCK1ESRRGHDAC1HDAC3
	SCHEMBL4919514	0.83	ESRRG (0.58)	ROCK2ROCK1ESRRGHDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.