SCHEMBL4919982

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4932478	0.89	ROCK1 (0.60)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4928076	0.88	ESRRG (0.58)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4919273	0.87	ROCK1 (0.58)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4928319	0.86	ROCK1 (0.70)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4928094	0.85	ROCK2 (0.68)	ROCK1ROCK2PRKACA
	SCHEMBL4928176	0.85	ROCK2 (0.57)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL12495978	0.84	EGLN2 (0.56)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4930353	0.84	ROCK1 (0.67)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL14100093	0.83	ROCK1 (0.54)	ROCK1ROCK2PRKACAPRKXPRKCQ
	SCHEMBL4930312	0.83	ESRRG (0.74)	ROCK1ROCK2PRKACAPRKXGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.