SCHEMBL4928207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4919806	1.00	ROCK1 (0.73)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL4923395	0.85	ROCK1 (1.00)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL4929608	0.85	ROCK1 (1.00)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL4929435	0.84	HDAC1 (0.69)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL14007253	0.81	HDAC1 (0.61)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL14007225	0.81	HDAC1 (0.61)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL12423603	0.79	HDAC3 (0.50)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL4929904	0.78	HDAC3 (0.57)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL4924499	0.78	HDAC3 (0.57)	ROCK1PRKACAGSK3AGSK3BRPS6KA3
	SCHEMBL8269793	0.78	HDAC3 (1.00)	HDAC1HDAC3HDAC4HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.