Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784893 | 0.94 | CYP19A1 (0.45) | PIK3CAPIK3CGPIK3CBCYP19A1MAPK10 | |
| SCHEMBL4738283 | 0.82 | MEN1 (0.59) | PIK3CAPIK3CGPIK3CBCYP19A1STS | |
| SCHEMBL4735908 | 0.82 | PIK3CG (0.69) | PIK3CAPIK3CGPIK3CBDYRK1ACLK4 | |
| SCHEMBL4909096 | 0.82 | PIK3CG (0.59) | PIK3CAPIK3CGPIK3CBDYRK1ACLK4 | |
| SCHEMBL4795643 | 0.80 | PRKCA (0.54) | PIK3CAPIK3CGPIK3CBMEN1NPC1 | |
| SCHEMBL4733854 | 0.79 | PLK1 (0.58) | CYP19A1MAPK10MEN1NPC1RAB9A | |
| SCHEMBL4735369 | 0.77 | MAPK10 (0.49) | CYP19A1MAPK10MEN1NPC1RAB9A | |
| SCHEMBL4732923 | 0.77 | CDK5 (0.52) | PIK3CAPIK3CGPIK3CBMEN1NPC1 | |
| SCHEMBL4732826 | 0.76 | JAK2 (0.59) | PIK3CAPIK3CGPIK3CBCLK4CLK1 | |
| SCHEMBL4909103 | 0.75 | PLK1 (0.50) | CYP19A1MAPK10PLK1KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153822-A1 | Methods of treating pain | INGENIUM PHARMACEUTICALS GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153822-A1 | Methods of treating pain | OPRL1, ACHE, OPRK1 | PIK3CA 4390/4885PIK3CG 4311/4885PIK3CB 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.