SCHEMBL4928672

SCHEMBL4928672

Cc1c(N)cc2cc3ccccc3cc2c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
CYP3A4 P08684 4/20 0.40
HSD17B10 Q99714 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HBB P68871 1/20 0.40
HIF1A Q16665 1/20 0.40
IDO1 P14902 1/20 0.38
NQO1 P15559 1/20 0.38
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
GAA P10253 2/20 0.37
POLB P06746 2/20 0.37
NCF1 P14598 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
GLA P06280 1/20 0.37
PTBP1 P26599 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4927955 0.83 TSHR (0.46) ALDH1A1CYP3A4HSD17B10TDP1CASP1
SCHEMBL22507712 0.82 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL797237 0.82 NQO1 (0.46) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL5749374 0.79 ALDH1A1 (0.45) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL1538428 0.78 CYP1A2 (0.41) ALDH1A1HSD17B10TDP1HIF1ANQO1
SCHEMBL29512148 0.78 CYP1A2 (0.41) ALDH1A1HSD17B10TDP1HIF1ANQO1
SCHEMBL7692618 0.78 ALDH1A1 (0.39) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL22776396 0.77 ALDH1A1 (0.50) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL687284 0.77 NQO1 (0.46) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL7501835 0.77 NQO1 (0.46) ALDH1A1CYP3A4HSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
EP-1840399-B1 COLLAPSIBLE COLUMN NSK LTD (JP) 2014-06-18 EP disclosed
CN-100591938-C Telescopic shaft NSK LTD 2010-02-24 CN disclosed
US-20080125231-A1 Telescopic Shaft NSK LTD. (JP) 2008-05-29 US disclosed
CN-101091069-A Collapsible column NSK LTD (JP) 2007-12-19 CN disclosed
EP-1840399-A1 COLLAPSIBLE COLUMN NSK Ltd., (JP) 2007-10-03 EP disclosed
US-7265080-B2 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. (JP) 2007-09-04 US disclosed
US-20060252654-A1 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. 2006-11-09 US disclosed
US-20060252655-A1 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. 2006-11-09 US disclosed
US-20060073989-A1 Grease compostion for automobile electrical equipment auxiliary device and prelubricated rolling using the grease composition NSK LTD. (JP) 2006-04-06 US disclosed
CN-1723270-A Grease composition for automobile electrical equipment auxiliary device and prelubricated rolling bearing using the grease composition NSK LTD (JP) 2006-01-18 CN disclosed
US-20050261141-A1 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. 2005-11-24 US disclosed
US-6919301-B2 Grease composition and rolling apparatus NSK LTD. (JP) 2005-07-19 US disclosed
US-20030176298-A1 Grease composition and rolling apparatus NSK LTD. (JP) 2003-09-18 US disclosed