SCHEMBL4928707

SCHEMBL4928707

O[C@@H]1[C@H](O[C@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@@H]2O)O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GJB2 P29033 3/20 0.57
NT5E P21589 1/20 0.53
SLC6A2 P23975 2/20 0.52
PTPN1 P18031 8/20 0.51
PTPN2 P17706 3/20 0.51
PTPN11 Q06124 3/20 0.51
SSTR1 P30872 1/20 0.49
SSTR2 P30874 1/20 0.49
SSTR4 P31391 1/20 0.49
SSTR3 P32745 1/20 0.49
SSTR5 P35346 1/20 0.49
GJA1 P17302 1/20 0.48
HTR1A P08908 1/20 0.48
CDC25B P30305 6/20 0.48
PTPN6 P29350 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4909410 1.00 GJB2 (0.57) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL8221413 0.93 NT5E (0.54) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL10523689 0.93 NT5E (0.54) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL977852 0.93 NT5E (0.54) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL18744555 0.93 NT5E (0.54) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL10523693 0.93 NT5E (0.54) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL11311474 0.92 SLC6A2 (0.53) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL5314955 0.91 GJB2 (0.55) GJB2NT5ESLC6A2PTPN1PTPN2
SCHEMBL23705129 0.90 SSTR1 (0.58) GJB2NT5EPTPN1PTPN2PTPN11
SCHEMBL17665036 0.90 SSTR1 (0.58) GJB2NT5EPTPN1PTPN2PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080193481-A1 Synthetic Anti-Candida Albicans Oligosaccharide Based Vaccines GOVERNORS OF THE UNIVERSITY OF ALBERTA 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193481-A1 Synthetic Anti-Candida Albicans Oligosaccharide Based Vaccines DDOST, FUT5, STT3B GJB2 2649/4885NT5E 3272/4885SLC6A2 4614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.