Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CTPS1 | P17812 | 4/20 | 0.49 |
| ▸ | RAF1 | P04049 | 2/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14069855 | 0.90 | KCNJ5 (0.56) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14069860 | 0.89 | BLM (0.49) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14069895 | 0.86 | MAPT (0.52) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL4933898 | 0.85 | DHODH (0.52) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14640549 | 0.85 | CYP1A2 (0.53) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14070045 | 0.84 | DHODH (0.51) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14069875 | 0.83 | MAPT (0.53) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL4933637 | 0.83 | MAPT (0.47) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL14069894 | 0.83 | DHODH (0.52) | MAPTCTPS1KCNJ5KCNJ3KMT2A | |
| SCHEMBL5591452 | 0.83 | MAPT (0.54) | MAPTCTPS1KCNJ5KCNJ3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221088-A1 | 3,4-Substituted Thiazoles as Ampk Activators | DR. REDDY'S LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
| US-20080221088-A1 | 3,4-Substituted Thiazoles as Ampk Activators | DR. REDDY'S LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
| US-20080221088-A1 | 3,4-Substituted Thiazoles as Ampk Activators | DR. REDDY'S LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221088-A1 | 3,4-Substituted Thiazoles as Ampk Activators | PRKAG3, PRKAG1, PRKAG2 | MAPT 2742/4885CTPS1 510/4885RAF1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.