SCHEMBL4929239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4932331	0.88	DYRK1A (0.59)	AKT3NPC1MAPK1ACKR3HDAC3
	SCHEMBL4931303	0.87	ACKR3 (0.57)	AKT3RAB9AACKR3HDAC3HDAC4
	SCHEMBL4929313	0.87	AKT3 (0.62)	AKT3SMN1; SMN2NPC1RAB9AMAPK1
	SCHEMBL4923388	0.87	ACKR3 (0.67)	AKT3SMN1; SMN2NPC1RAB9AACKR3
	SCHEMBL4931503	0.86	HDAC3 (0.56)	AKT3SMN1; SMN2NPC1RAB9AHTT
	SCHEMBL4926933	0.86	ACKR3 (0.57)	AKT3SMN1; SMN2NPC1RAB9AACKR3
	SCHEMBL4919672	0.86	ACKR3 (0.59)	AKT3SMN1; SMN2NPC1RAB9AACKR3
	SCHEMBL4931299	0.85	HDAC6 (0.64)	AKT3SMN1; SMN2NPC1RAB9AACKR3
	SCHEMBL4925079	0.84	ACKR3 (0.58)	AKT3SMN1; SMN2NPC1RAB9AKMT2A
	SCHEMBL4929448	0.84	ACKR3 (0.53)	AKT3SMN1; SMN2MAPK1ACKR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.