SCHEMBL4929313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4931299	0.91	HDAC6 (0.64)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4929439	0.89	HDAC2 (0.58)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4932455	0.88	AKT3 (0.62)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4926727	0.88	NPC1 (0.59)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4927704	0.88	AKT3 (0.62)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4923388	0.88	ACKR3 (0.67)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4929239	0.87	AKT3 (0.66)	AKT3NPC1RAB9AHDAC3HDAC4
	SCHEMBL4929057	0.85	ACKR3 (0.57)	AKT3NPC1HDAC3HDAC4HDAC1
	SCHEMBL4928129	0.84	KMT2A (0.65)	AKT3NPC1HDAC3HDAC4HDAC1
	SCHEMBL4925690	0.83	ACKR3 (0.57)	AKT3RAB9AHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.