Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | FEN1 | P39748 | 8/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229922 | 0.90 | TDO2 (0.35) | TDO2 | |
| SCHEMBL27542494 | 0.85 | TDO2 (0.44) | TDO2FEN1ATRALOX5APADK | |
| SCHEMBL1320584 | 0.74 | TDO2 (0.46) | TDO2FEN1ALOX5AP | |
| SCHEMBL3450475 | 0.74 | TDO2 (0.46) | TDO2FEN1ALOX5AP | |
| SCHEMBL5775480 | 0.74 | TDO2 (0.42) | TDO2FEN1ALOX5APCCNE1CDK2 | |
| SCHEMBL5776718 | 0.74 | TDO2 (0.42) | TDO2FEN1ALOX5APCCNE1CDK2 | |
| SCHEMBL2789204 | 0.74 | TDO2 (0.46) | TDO2FEN1ATRALOX5APADK | |
| SCHEMBL5776461 | 0.74 | TDO2 (0.42) | TDO2FEN1ALOX5APCCNE1CDK2 | |
| SCHEMBL2787969 | 0.72 | TDO2 (0.44) | TDO2FEN1ATRALOX5APADK | |
| SCHEMBL1318378 | 0.72 | TDO2 (0.44) | TDO2FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | MCHR1, GPR119, MCHR2 | TDO2 1267/4885FEN1 4555/4885ATR 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.