Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717903 | 0.95 | THRA (0.37) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4926320 | 0.90 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL5110779 | 0.89 | MEN1 (0.39) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4358827 | 0.89 | THRA (0.41) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4924012 | 0.89 | HSD17B10 (0.38) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4927726 | 0.89 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL4932562 | 0.88 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4932166 | 0.87 | HSD17B10 (0.39) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL5109500 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ERAB9AMEN1 | |
| SCHEMBL4525572 | 0.86 | KDM4E (0.41) | ALDH1A1GAAKDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | ALDH1A1 1818/4885GAA 4551/4885KDM4E 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.