Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929596 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CYP3A4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1928886 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CYP3A4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1928889 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CYP3A4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4488303 | 0.84 | NR1H2 (0.33) | SLC1A3SLC1A2SLC1A1SLC16A3SLC16A1 | |
| SCHEMBL4488309 | 0.84 | NR1H2 (0.33) | SLC1A3SLC1A2SLC1A1SLC16A3SLC16A1 | |
| SCHEMBL4926051 | 0.84 | NR1H2 (0.33) | SLC1A3SLC1A2SLC1A1SLC16A3SLC16A1 | |
| SCHEMBL4926067 | 0.84 | NR1H2 (0.33) | SLC1A3SLC1A2SLC1A1SLC16A3SLC16A1 | |
| SCHEMBL1928447 | 0.83 | CHRM2 (0.36) | ALDH1A1CYP3A4 | |
| SCHEMBL1929339 | 0.83 | CHRM2 (0.36) | ALDH1A1CYP3A4 | |
| SCHEMBL1928444 | 0.83 | CHRM2 (0.36) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015238-A1 | CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-17 | — | — | US | disclosed |
| US-7259177-B2 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
| US-20050101637-A1 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015238-A1 | CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | GPR119, PC, ACADM | ALDH1A1 268/4885CYP3A4 311/4885SLC1A3 874/4885 |
| US-20050101637-A1 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | GPR119, PC, CPT1A | ALDH1A1 212/4885CYP3A4 244/4885SLC1A3 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.