Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919464 | 0.73 | — | — | |
| SCHEMBL1768613 | 0.69 | NOS2 (0.37) | — | |
| SCHEMBL4934437 | 0.63 | SMN1; SMN2 (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3639242 | 0.63 | ADRA1D (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4925041 | 0.62 | ICAM1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1224893 | 0.61 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4930064 | 0.61 | SMN1; SMN2 (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3636288 | 0.61 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2429717 | 0.60 | KDM4A (0.31) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1559800 | 0.60 | MAP4K1 (0.38) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | ALDH1A1 185/4885HPGD 80/4885SMN1; SMN2 3713/4885 |
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | ALDH1A1 111/4885HPGD 39/4885SMN1; SMN2 3490/4885 |
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | ALDH1A1 248/4885HPGD 1996/4885SMN1; SMN2 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.