Sugi Predict

Sugi Predict / Compounds / SCHEMBL4930458

SCHEMBL4930458

SCHEMBL4930458

Cn1cc(C(=O)Nc2ccccc2)c(C(F)F)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ NAMPT P43490 1/20 0.49
▸ LMNA P02545 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ AURKA O14965 4/20 0.48
▸ TP53 P04637 1/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.46
▸ BCAT2 O15382 1/20 0.46
▸ HPGD P15428 1/20 0.45
▸ HTT P42858 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15561466 0.89 ALDH1A1 (0.54) RAB9ASMN1; SMN2CYP2C9CYP1A2GAA
SCHEMBL12251750 0.88 GAA (0.52) RAB9ASMN1; SMN2CYP2C9CYP1A2GAA
SCHEMBL22029356 0.87 SMN1; SMN2 (0.50) RAB9ASMN1; SMN2NAMPTPOLBAURKA
SCHEMBL22029381 0.86 ALDH1A1 (0.53) RAB9ASMN1; SMN2GAANAMPTLMNA
SCHEMBL18106786 0.86 LMNA (0.48) RAB9ASMN1; SMN2CYP1A2NAMPTLMNA
SCHEMBL28348101 0.84 ATM (0.49) RAB9ASMN1; SMN2GAALMNAPOLB
SCHEMBL20584163 0.84 CNR2 (0.47) RAB9ASMN1; SMN2NAMPTLMNAPOLB
SCHEMBL20543320 0.83 NAMPT (0.42) RAB9ASMN1; SMN2NAMPTLMNAPOLB
SCHEMBL21652213 0.83 P2RX1 (0.49) SMN1; SMN2NAMPTTP53MEN1KMT2A
SCHEMBL18117496 0.83 NPC1 (0.49) RAB9ASMN1; SMN2LMNATP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2880013-B1 METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS USING C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2018-05-09 — — EP claimed
US-9199915-B2 Process for preparing substituted biphenyls by C-H activation BAYER CROPSCIENCE AG (DE) 2015-12-01 — — US claimed
US-20150203440-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2015-07-23 — — US claimed
EP-2880013-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION Bayer CropScience AG (DE) 2015-06-10 — — EP claimed
WO-2014019995-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2014-02-06 — — WO claimed
EP-3677572-B1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE JAPAN FINECHEM COMPANY INC (JP) 2023-06-07 — — EP disclosed
US-11033029-B2 Pyrazole amide compound and use thereof SHENYANG SINOCHEM AGROCHEMICALS R & D CO., LTD. (CN) 2021-06-15 — — US disclosed
US-20200221699-A1 PYRAZOLE AMIDE COMPOUND AND USE THEREOF JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2020-07-16 — — US disclosed
EP-3677572-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE Japan Finechem Company, Inc. (JP) 2020-07-08 — — EP disclosed
US-20200181091-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE JAPAN FINECHEM COMPANY, INC. (JP) 2020-06-11 — — US disclosed
CN-110891940-A Process for preparing pyrazole-4-carboxamide derivatives 日本凡凯姆股份有限公司 2020-03-17 — — CN disclosed
WO-2018201272-A1 PROCESS FOR THE MANUFACTURE OF CARBOXYLIC ACIDS OR CARBOXYLIC ACID DERIVATIVES SOLVAY FLUOR GMBH (DE) 2018-11-08 — — WO disclosed
EP-3075727-A1 PYRAZOLE AMIDE COMPOUND AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2016-10-05 — — EP disclosed
US-9199915-B2 Process for preparing substituted biphenyls by C-H activation BAYER CROPSCIENCE AG (DE) 2015-12-01 — — US disclosed
US-20150203440-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2015-07-23 — — US disclosed
EP-2880013-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION Bayer CropScience AG (DE) 2015-06-10 — — EP disclosed
WO-2014019995-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2014-02-06 — — WO disclosed
CN-102143689-A Use of fungicidal compound compositions for controlling certain rust fungi BAYER CROPSCIENCE AG 2011-08-03 — — CN disclosed
US-20080108686-A1 N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides BASF AKTIENGESELLSCHAFT (DE) 2008-05-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11033029-B2 Pyrazole amide compound and use thereof NAT1, C9, AADAC RAB9A 787/4885SMN1; SMN2 4131/4885CYP2C9 221/4885
US-20200181091-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE AADAC, CYP3A4, ABAT RAB9A 3227/4885SMN1; SMN2 3913/4885CYP2C9 28/4885
US-20080108686-A1 N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides CBR3, DDT, CBR1 RAB9A 2293/4885SMN1; SMN2 2231/4885CYP2C9 80/4885
US-20200221699-A1 PYRAZOLE AMIDE COMPOUND AND USE THEREOF NAT1, C9, AADAC RAB9A 787/4885SMN1; SMN2 4131/4885CYP2C9 221/4885
US-20150203440-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION CYP1A1, CBR1, AHR RAB9A 2089/4885SMN1; SMN2 3884/4885CYP2C9 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.