Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029356 | 0.86 | SMN1; SMN2 (0.50) | TSHRHTTNAMPTSMN1; SMN2MEN1 | |
| SCHEMBL18106786 | 0.85 | LMNA (0.48) | HTTNAMPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL22029381 | 0.85 | ALDH1A1 (0.53) | RXFP1NAMPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4930458 | 0.83 | RAB9A (0.50) | HTTNAMPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL20584163 | 0.83 | CNR2 (0.47) | NAMPTSMN1; SMN2 | |
| SCHEMBL21652175 | 0.83 | LMNA (0.62) | P2RX1HDAC3HDAC8HDAC6RXFP1 | |
| SCHEMBL21652221 | 0.82 | CCR1 (0.46) | NR1H4 | |
| SCHEMBL20543320 | 0.82 | NAMPT (0.42) | NAMPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18117496 | 0.82 | NPC1 (0.49) | TSHRTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15561466 | 0.78 | ALDH1A1 (0.54) | NAMPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | P2RX1 4712/4885HDAC3 3413/4885HDAC8 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.