Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933385 | 0.90 | MEN1 (0.39) | KMT2AMEN1FFAR1ALDH1A1KDM4E | |
| SCHEMBL4929570 | 0.90 | FFAR1 (0.35) | KMT2AMEN1FFAR1ALDH1A1KDM4E | |
| SCHEMBL5718054 | 0.88 | MEN1 (0.38) | KMT2AMEN1FFAR1ALDH1A1KDM4E | |
| SCHEMBL5718015 | 0.87 | MEN1 (0.36) | KMT2AMEN1FFAR1TACR1MRGPRX4 | |
| SCHEMBL4932565 | 0.87 | MRGPRX4 (0.41) | TACR1MRGPRX4S1PR1 | |
| SCHEMBL4934576 | 0.85 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4EOPRK1 | |
| SCHEMBL4935426 | 0.85 | FFAR1 (0.39) | KMT2AMEN1FFAR1ALDH1A1HTT | |
| SCHEMBL4931768 | 0.84 | FFAR1 (0.40) | KMT2AFFAR1ALDH1A1KDM4EMAPT | |
| SCHEMBL4931110 | 0.84 | CRHR1 (0.36) | FFAR1TACR1MRGPRX4S1PR1 | |
| SCHEMBL4531944 | 0.83 | THRA (0.45) | KMT2AMEN1FFAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | KMT2A 1742/4885MEN1 773/4885FFAR1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.