SCHEMBL4931342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14849810	0.89	NPC1 (1.00)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL23091256	0.86	NPC1 (0.76)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL4930772	0.86	ESRRG (0.73)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764358	0.84	HDAC3 (0.58)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764056	0.84	ESRRG (1.00)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764243	0.83	HDAC3 (0.61)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764061	0.83	NPC1 (0.75)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL4929228	0.82	SMN1; SMN2 (0.82)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764045	0.82	IDE (0.62)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL20764069	0.82	ESRRG (0.74)	NPC1RAB9APPARGNCOA2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.