Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931285 | 0.92 | ALDH1A1 (0.37) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL4947897 | 0.91 | KMT2A (0.39) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL4929941 | 0.90 | SMN1; SMN2 (0.38) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL4933336 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL4931300 | 0.89 | ALDH1A1 (0.37) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL5116899 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL5717983 | 0.88 | THRA (0.43) | THRB | |
| SCHEMBL5107711 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL5718235 | 0.87 | ALDH1A1 (0.34) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL4935198 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | ALDH1A1 1818/4885KMT2A 1742/4885HPGD 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.