SCHEMBL4932475

SCHEMBL4932475

Nc1cccc2c1C(N)c1ccccc1S2

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GRM1 Q13255 3/20 0.32
GRM5 P41594 2/20 0.32
PTPN5 P54829 1/20 0.32
HTR2A P28223 1/20 0.31
TSHR P16473 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88255 0.80 HTR2A (0.46) CYP3A4ALOX15GRM1GRM5HTR2A
SCHEMBL15738068 0.74 KDM1A (0.39) CYP3A4GRM1GRM5TSHRCYP2D6
SCHEMBL28791725 0.73 HTR2A (0.33) ALOX15GRM1GRM5HTR2ATSHR
SCHEMBL29557747 0.71 ALDH1A1 (0.42) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrochloric Acid SCHEMBL7927089 0.69 ALDH1A1 (0.41) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL13319391 0.68 HTR2A (0.35) GRM1GRM5HTR2ACYP2D6
SCHEMBL1461768 0.67 MAOA (0.44) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL1503444 0.66 GPR3 (0.38) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL4001467 0.66 BCHE (0.46) CYP3A4SMN1; SMN2TSHRCYP2D6
Hydrochloric Acid SCHEMBL5350636 0.66 ALDH1A1 (0.40) CYP3A4ALOX15GRM1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP claimed
EP-0390992-B1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES (JP) 1994-06-01 EP claimed
US-5141642-A Separators for reverse osmosis, ultrafiltration, dehydration, heat and chemical resistance, strength, gas permeability UBE INDUSTRIES, LTD. (JP) 1992-08-25 US claimed
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US claimed
EP-0390992-A1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US claimed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP claimed
US-7339009-B2 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY (US) 2008-03-04 US disclosed
US-20060135732-A1 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP disclosed
EP-0446947-B1 Gas separating asymmetric membrane UBE INDUSTRIES (JP) 1995-05-24 EP disclosed
EP-0390992-B1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES (JP) 1994-06-01 EP disclosed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0390992-A1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US disclosed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP disclosed
EP-0263212-A1 Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-04-13 EP disclosed
US-4718921-A Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-01-12 US disclosed