Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KDM6B | O15054 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16466448 | 0.81 | TDP1 (0.50) | KDM4EKDM6BKDM4CALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL21405660 | 0.76 | LMNA (0.40) | ALDH1A1LMNAHTTSMN1; SMN2AKR1C3 | |
| SCHEMBL372487 | 0.76 | LMNA (0.40) | ALDH1A1LMNAHTTSMN1; SMN2AKR1C3 | |
| SCHEMBL31357901 | 0.76 | LMNA (0.40) | ALDH1A1LMNAHTTSMN1; SMN2AKR1C3 | |
| SCHEMBL492479 | 0.76 | CYP1A2 (0.47) | ALDH1A1THRBMEN1MAPTKMT2A | |
| SCHEMBL492480 | 0.76 | CYP1A2 (0.47) | ALDH1A1THRBMEN1MAPTKMT2A | |
| SCHEMBL28032461 | 0.73 | MAPT (0.42) | KDM4EALDH1A1THRBTDP1MEN1 | |
| SCHEMBL4024273 | 0.73 | TRPV1 (0.49) | KDM4EMAPTLMNA | |
| SCHEMBL31149008 | 0.72 | HSD17B10 (0.41) | KDM4EALDH1A1THRBTDP1MEN1 | |
| SCHEMBL1226388 | 0.72 | LMNA (0.57) | KDM4ETHRBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106066-B2 | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2012-01-31 | — | — | US | disclosed |