Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21405660 | 1.00 | LMNA (0.40) | LMNAHSD17B10HTR1AADRA1AALDH1A1 | |
| SCHEMBL31357901 | 1.00 | LMNA (0.40) | LMNAHSD17B10HTR1AADRA1AALDH1A1 | |
| SCHEMBL29154198 | 0.88 | ALDH1A1 (0.43) | LMNAHSD17B10HTR1AADRA1AALDH1A1 | |
| SCHEMBL1162115 | 0.86 | PPARG (0.39) | HSD17B10ADRA1AALDH1A1KYNUTSHR | |
| SCHEMBL19951679 | 0.86 | PPARG (0.39) | HSD17B10ADRA1AALDH1A1KYNUTSHR | |
| Methane SCHEMBL28344019 | 0.84 | PPARG (0.38) | HSD17B10ADRA1AALDH1A1KYNUTSHR | |
| SCHEMBL1667994 | 0.83 | CPN1 (0.36) | LMNAHSD17B10HTR1AADRA1AALDH1A1 | |
| SCHEMBL372364 | 0.83 | ALDH1A1 (0.42) | HSD17B10ALDH1A1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL31357789 | 0.82 | HSD17B10 (0.38) | LMNAHSD17B10ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16586532 | 0.82 | ALDH1A1 (0.42) | HSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343678-A1 | METHOD FOR SYNTHESIZING 5,8-DIAMINO-3,4-DIHYDRO-2H-1-NAPHTHALENONE AND INTERMEDIATE COMPOUND USED THEREIN | JIANGSU MABWELL HEALTH PHARMACEUTICAL R&D CO., LTD. (CN) | 2024-10-17 | — | — | US | claimed |
| EP-4389732-A1 | METHOD FOR SYNTHESIZING 5,8-DIAMINO-3,4-DIHYDRO-2H-1-NAPHTHALENONE AND INTERMEDIATE COMPOUND USED THEREIN | Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. (CN) | 2024-06-26 | — | — | EP | claimed |
| WO-2023238126-A1 | COMPOSITION AND METHOD FOR USE THEREOF FOR TREATMENT AND PREVENTION OF AUTOIMMUNE AND NEUROLOGICAL DISORDERS | LEVICURE LTD (IL) | 2023-12-14 | — | — | WO | claimed |
| EP-3059004-B1 | METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION | BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) | 2021-06-30 | — | — | EP | claimed |
| US-9999852-B2 | Method for removing SOx from gas with compound alcohol-amine solution | BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO., LTD (CN) | 2018-06-19 | — | — | US | claimed |
| CN-105418966-B | A kind of rubber additive and its preparation and application | 同济大学 | 2017-12-15 | — | — | CN | claimed |
| CN-106456662-A | Compositions of pentosan polysulfate for oral administration and methods of use thereof | 奥利金制药公司 | 2017-02-22 | — | — | CN | claimed |
| US-20160243491-A1 | Method for Removing SOx from Gas with Compound Alcohol-Amine Solution | PEKING UNIVERSITY (CN) | 2016-08-25 | — | — | US | claimed |
| EP-3059004-A1 | METHOD FOR REMOVING SOX FROM GAS WITHNCOMPOUND ALCOHOL-AMINE SOLUTION | Beijing Boyuan-Hengsheng High-Technology Co., Ltd. (CN) | 2016-08-24 | — | — | EP | claimed |
| CN-105418966-A | Rubber additive and preparation and application thereof | UNIV TONGJI | 2016-03-23 | — | — | CN | claimed |
| US-5731285-A | Tachiquinine antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds | A. MENATINI INDUSTRIE FARMACEUTICHE (IT) | 1998-03-24 | — | — | US | claimed |
| EP-0815126-A1 | BICYCLIC TACHYKININS ANTAGONISTS, PREPARATION THEREOF AND THEIR USE IN PHARMACEUTICAL COMPOSITION | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-01-07 | — | — | EP | claimed |
| WO-1997031938-A9 | OLIGOPEPTIDES FOR DRUG DELIVERY | — | 1997-11-20 | — | — | WO | claimed |
| WO-1997031938-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-09-04 | — | — | WO | claimed |
| EP-0636146-B1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | MENARINI FARMA IND (IT) | 1997-07-30 | — | — | EP | claimed |
| WO-1996028467-A1 | BICYCLIC TACHYKININS ANTAGONISTS, PREPARATION THEREOF AND THEIR USE IN PHARMACEUTICAL COMPOSITION | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1996-09-19 | — | — | WO | claimed |
| EP-0672678-A1 | Azapeptide derivative | FUJIREBIO Inc. (JP) | 1995-09-20 | — | — | EP | claimed |
| EP-0636146-A1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS. | MENARINI FARMA IND (IT) | 1995-02-01 | — | — | EP | claimed |
| CN-1080916-A | The quinic tricyclic compound of anti-column foot, its preparation method and contain the pharmaceutical composition of this compound | MENARINI FARMA IND (IT) | 1994-01-19 | — | — | CN | claimed |
| WO-1993021227-A1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1993-10-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343678-A1 | METHOD FOR SYNTHESIZING 5,8-DIAMINO-3,4-DIHYDRO-2H-1-NAPHTHALENONE AND INTERMEDIATE COMPOUND USED THEREIN | CCKBR, DDC, DHPS | LMNA 978/4885HSD17B10 298/4885HTR1A 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.