SCHEMBL4932819

SCHEMBL4932819

CNc1cc(C)cc(COc2c(Cl)cc(CCC(=O)O)cc2Cl)c1F

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 12/20 0.44
FFAR1 O14842 8/20 0.44
THRA P10827 8/20 0.44
THRB P10828 8/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4929663 0.90 THRA (0.42) FFAR4FFAR1THRATHRB
SCHEMBL5112307 0.89 FFAR4 (0.43) FFAR4FFAR1THRATHRB
SCHEMBL4930725 0.89 THRA (0.44) FFAR4FFAR1THRATHRB
SCHEMBL4931849 0.89 THRA (0.58) FFAR4FFAR1THRATHRB
SCHEMBL4926366 0.89 THRB (0.41) FFAR4FFAR1THRATHRB
SCHEMBL4926593 0.89 FFAR4 (0.42) FFAR4FFAR1THRATHRB
SCHEMBL5106646 0.88 THRA (0.42) FFAR4FFAR1THRATHRB
SCHEMBL5116495 0.88 THRA (0.43) FFAR4FFAR1THRATHRB
SCHEMBL4934279 0.88 FFAR4 (0.41) FFAR4FFAR1THRATHRB
SCHEMBL5112507 0.87 FFAR4 (0.41) FFAR4FFAR1THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080221210-A1 Thyroid Receptor Agonists KARO BIO AB (SE) 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221210-A1 Thyroid Receptor Agonists TSHR, TRHR, THRA FFAR4 65/4885FFAR1 37/4885THRA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.