Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.42 |
| ▸ | RHOC | P08134 | 3/20 | 0.37 |
| ▸ | RHOA | P61586 | 3/20 | 0.37 |
| ▸ | CCR2 | P41597 | 3/20 | 0.35 |
| ▸ | USP5 | P45974 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717942 | 0.96 | MRGPRX4 (0.39) | MRGPRX4RHOCRHOACCR2USP5 | |
| SCHEMBL4929949 | 0.91 | THRA (0.41) | MRGPRX4RHOCRHOACCR2USP5 | |
| SCHEMBL5717949 | 0.89 | MRGPRX4 (0.39) | MRGPRX4RHOCRHOACCR2 | |
| SCHEMBL4931877 | 0.88 | PDE4A (0.35) | MRGPRX4USP5 | |
| SCHEMBL4926882 | 0.88 | PDE4A (0.36) | MRGPRX4USP5 | |
| SCHEMBL4931806 | 0.86 | F2 (0.39) | USP5 | |
| SCHEMBL4932229 | 0.85 | PPARD (0.43) | MRGPRX4RHOCRHOA | |
| SCHEMBL4922986 | 0.85 | CRHR1 (0.43) | MRGPRX4RHOCRHOACCR2 | |
| SCHEMBL4923555 | 0.85 | MRGPRX4 (0.41) | MRGPRX4RHOCRHOA | |
| SCHEMBL4932213 | 0.84 | MRGPRX4 (0.43) | MRGPRX4RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | MRGPRX4 119/4885RHOC 1793/4885RHOA 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.