Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937425 | 0.93 | GAA (0.55) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL4933227 | 0.91 | KCNH2 (0.63) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL3534383 | 0.86 | HRH3 (0.59) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL4940759 | 0.85 | GAA (0.61) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL2974984 | 0.84 | DRD2 (0.59) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL4932782 | 0.83 | CHRNB2 (0.61) | KCNH2MAPTLTA4HPTGS2 | |
| SCHEMBL1735227 | 0.81 | KCNH2 (0.55) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL10554981 | 0.81 | HRH3 (0.69) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL9570561 | 0.81 | HRH3 (0.69) | KCNH2HRH3DRD2DRD4DRD3 | |
| SCHEMBL5390369 | 0.81 | HRH3 (0.69) | KCNH2HRH3DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | KCNH2 2174/4885HRH3 3448/4885DRD2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.