Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974984 | 0.92 | DRD2 (0.59) | KCNH2DRD2DRD4DRD3MAPT | |
| P-Nitrophenol SCHEMBL7697743 | 0.92 | MAPT (0.51) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL3534383 | 0.91 | HRH3 (0.59) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL7955666 | 0.90 | ALDH1A1 (0.56) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL6228523 | 0.88 | MAPT (0.65) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL9570575 | 0.86 | DRD2 (0.65) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL10554981 | 0.84 | HRH3 (0.69) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL9570561 | 0.84 | HRH3 (0.69) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL10501147 | 0.84 | LMNA (0.54) | KCNH2DRD2DRD4DRD3MAPT | |
| SCHEMBL10558691 | 0.84 | HRH3 (0.69) | KCNH2DRD2DRD4DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257069-A1 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2025-08-14 | — | — | US | disclosed |
| CN-119923257-A | JAK inhibitor analogues, formulations and uses thereof | 密歇根大学董事会 | 2025-05-02 | — | — | CN | disclosed |
| WO-2023201044-A2 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-10-19 | — | — | WO | disclosed |
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |
| CN-109593064-B | Dithiocarbamate compounds as BTK inhibitors | 北京博远精准医疗科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-110950781-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2020-04-03 | — | — | CN | disclosed |
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
| US-20180362450-A1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2018-12-20 | — | — | US | disclosed |
| EP-3395795-A1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-10023530-B2 | Diamine, polyamic acid, and polyimide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| CN-87103300-A | Antiarrhythmic and preparation method thereof | — | 1987-11-11 | — | — | CN | disclosed |
| EP-0147973-A1 | Tetrazolcarboxanilid derivatives | Lilly Industries Limited (GB) | 1985-07-10 | — | — | EP | disclosed |
| US-4206144-A | N,N-Dialkyl-N-aminoalkyl-N-(amino or nitro)phenylalkyl- and N-methyl-N-[3-(amino or nitro)phenoxy-2-hydroxy-1-propyl]-N,N-bis(3-aminopropyl)quaternary ammonium salts | STERLING DRUG INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4146558-A | Azo dyestuff intermediate nitro- or aminobenzenes ring-substituted by a quaternized amine alkyl or amino-alkoxy group | STERLING DRUG INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4103092-A | Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs | STERLING DRUG INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4065500-A | Water-soluble quaternary ammonium azo dyestuffs | STERLING DRUG INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3996282-A | Water-soluble quaternary ammonium dyestuffs | STERLING DRUG INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |
| US-3935182-A | Water-soluble quaternary ammonium heterocyclic azo dyestuffs | STERLING DRUG INC. (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | KCNH2 3963/4885DRD2 3687/4885DRD4 1380/4885 |
| US-10023530-B2 | Diamine, polyamic acid, and polyimide | H1-2, H1-4, H1-0 | KCNH2 3803/4885DRD2 400/4885DRD4 191/4885 |
| US-20180362450-A1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | ME1, MAL2, ME3 | KCNH2 3963/4885DRD2 3687/4885DRD4 1380/4885 |
| US-20250257069-A1 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | JAK1, JAK3, JAK2 | KCNH2 4532/4885DRD2 4325/4885DRD4 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.