Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707105 | 0.98 | CTSK (0.54) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL1706617 | 0.98 | CTSK (0.54) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL1706616 | 0.98 | CTSK (0.54) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL27469415 | 0.87 | CTSK (0.52) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL22338678 | 0.87 | CTSK (0.48) | CTSKCTSSKMT2ATSHR | |
| SCHEMBL23845159 | 0.87 | HRH2 (0.48) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL9718051 | 0.87 | HRH2 (0.48) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL7352660 | 0.86 | MAPK1 (0.54) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL8717338 | 0.86 | ITGB3 (0.54) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL25186364 | 0.86 | ITGB3 (0.54) | CTSKCTSSITGB3ITGA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | FERRING B. V. | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | DPP4, DPP9, DPP3 | CTSK 490/4885CTSS 143/4885ITGB3 4014/4885 |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | CTSK 336/4885CTSS 95/4885ITGB3 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.