Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.54 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25186364 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL2896794 | 0.99 | ITGB3 (0.53) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL25183128 | 0.99 | ITGB3 (0.53) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL7298353 | 0.89 | CYP2D6 (0.46) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL25177957 | 0.86 | CTSK (0.48) | ITGB3ITGA2BTSHRCTSKCTSS | |
| SCHEMBL4933439 | 0.86 | CTSK (0.52) | ITGB3ITGA2BTSHRCTSKCTSS | |
| SCHEMBL25185744 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BTSHRCTSKCTSS | |
| SCHEMBL25186006 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL25186542 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BCALCRLTSHRCTSK | |
| SCHEMBL23845159 | 0.84 | HRH2 (0.48) | ITGB3ITGA2BTSHRCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |